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Anti-Fatty Acid Synthase Mouse mAb (100 μl)
| Reactivity: | H,M & M |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Fatty acid synthase |
Synonyms: | FASN, fatty acid synthase, Fasn,A630082H08Rik, FAS, OA-519, SDR27X1,Fatty acid synthase |
Immunogen: | Recombinant protein corresponding to Mouse Fatty acid synthase |
Uniprot ID: | P19096 |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. / Observed MW. | 273 kDa / 250-273 kDa |
Product Usage Information
WB | Human, Mouse | 1: 500-1: 1000 | brain |
IHC/IF | Mouse | 1: 1000-1: 2000 | lung |
Background
Fatty acid synthase is a multi-enzyme protein that catalyzes fatty acid synthesis. It is not a single enzyme but a whole enzymatic system composed of two identical 272 kDa multifunctional polypeptides, in which substrates are handed from one functional domain to the next. Its main function is to catalyze the synthesis of palmitate (C16:0, a long-chain saturated fatty acid) from acetyl-CoA and malonyl-CoA, in the presence of NADPH.
Images
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Western blot analysis of FASN (GB12547) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin embedded mouse lung using FASN (GB12547) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
