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| Reactivity: | Human |
| Applications: | FCM |
| Host Species: | Mouse |
| Isotype: | Mouse IgG1, κ |
| Clonality: | Monoclonal |
| Conjugation: | None (Purified antibody-Azide Free/Low endotoxin) |
| Synonyms: | Integrin alpha-L,LFA-1A,CD11A,ITGAL |
| Background: | CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50). |
| Gene ID: | 3683 |
| SwissProt: | P20701 |
| Concentration: | 0.5 mg/mL |
| Buffer: | 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
| Storage: | Store at 2~8°C. Do not freeze. |
| Documents: | Please contact us to request the manual |
