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Reactivity: | Human |
Applications: | FCM |
Host Species: | Mouse |
Isotype: | Mouse IgG1, κ |
Clonality: | Monoclonal |
Conjugation: | None (Purified antibody-Azide Free/Low endotoxin) |
Synonyms: | T-cell surface glycoprotein CD4,CD4,T-cell surface antigen T4/Leu-3,CD4 |
Background: | CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7). |
Gene ID: | 920 |
SwissProt: | P01730 |
Concentration: | 0.5 mg/mL |
Buffer: | 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
Storage: | Store at 2~8°C. Do not freeze. |
Documents: | Please contact us to request the manual |