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Reactivity: | Human |
Applications: | FCM |
Host Species: | Mouse |
Isotype: | Mouse IgG1, κ |
Clonality: | Monoclonal |
Conjugation: | AF647 |
Synonyms: | IL-3Rα, IL-3 Receptor alpha |
Background: | CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells. |
Gene ID: | 3563 |
SwissProt: | P26951 |
Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |
Documents: | Please contact us to request the manual |