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| Reactivity: | Human, Mouse |
| Applications: | FCM, IC |
| Host Species: | Rat |
| Isotype: | Rat IgG1, κ |
| Clonality: | Monoclonal |
| Conjugation: | APC |
| Synonyms: | Interleukin-5,IL-5,B-cell differentiation factor I,T-cell replacing factor,TRF |
| Background: | IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5. |
| Gene ID: | 3567,16191 |
| SwissProt: | P05113,P04401 |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. |
| Documents: | Please contact us to request the manual |
