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| Reactivity: | Mouse |
| Applications: | FCM, IC |
| Host Species: | Rat |
| Isotype: | Rat IgG2b, κ |
| Clonality: | Monoclonal |
| Conjugation: | APC |
| Synonyms: | Interleukin-10,IL-10,Cytokine synthesis inhibitory factor,CSIF |
| Background: | L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production); and promotes mast cell proliferation in combination with IL-4. |
| Gene ID: | 16153 |
| SwissProt: | P18893 |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. |
| Documents: | Please contact us to request the manual |
