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Reactivity: | Human |
Applications: | FCM |
Host Species: | Mouse |
Isotype: | Mouse IgG1, κ |
Clonality: | Monoclonal |
Conjugation: | Biotin |
Synonyms: | Integrin alpha-Iib,ITGA2B,GPalpha Iib,GPIIb,Platelet membrane glycoprotein Iib,CD41,GP2B, ITGAB |
Background: | CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin. |
Gene ID: | 3674 |
SwissProt: | P08514 |
Concentration: | 0.5 mg/mL |
Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2~8°C. Do not freeze. |
Documents: | Please contact us to request the manual |