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| Reactivity: | Human |
| Applications: | FCM |
| Host Species: | Mouse |
| Isotype: | Mouse IgG1, κ |
| Clonality: | Monoclonal |
| Conjugation: | Biotin |
| Synonyms: | L-selectin,Sell,CD62 antigen-like family member L,LAM-1,LECAM1,Lymph node homing receptor,Ly-22, CD62L,Lnhr,Ly22 |
| Background: | CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells. |
| Gene ID: | 6402 |
| SwissProt: | P14151 |
| Concentration: | 0.5 mg/mL |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Storage: | Store at 2~8°C. Do not freeze. |
| Documents: | Please contact us to request the manual |
