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| Reactivity: | Human |
| Applications: | FCM |
| Host Species: | Mouse |
| Isotype: | Mouse IgG1, κ |
| Clonality: | Monoclonal |
| Conjugation: | PE |
| Synonyms: | Interleukin-2 receptor subunit beta,IL-2RB,p75,CD122,IL-2Rβ |
| Background: | CD122 is a 70-75 kD type I transmembrane glycoprotein and member of the Ig superfamily. It is IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. CD122 is constitutively expressed by NK cells and at lower levels by a subset of T cells. Its expression is upregulated upon activation. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. |
| Gene ID: | 3560 |
| SwissProt: | P14784 |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |
| Documents: | Please contact us to request the manual |
