PE/Cyanine5.5 Anti-Human CD127/IL-7RA Antibody (20 T)

PE/Cyanine5.5 Anti-Human CD127/IL-7RA Antibody (20 T)

Cat. #: FD2683
Availability: In Stock
$289.00
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Reactivity: Human    
Applications: FCM    
Host Species: Mouse     
Isotype: Mouse IgG1, κ    
Clonality: Monoclonal    
Conjugation: PE/Cyanine5.5    
Synonyms: Interleukin-7 receptor subunit alpha,IL-7RA,CDw127,CD127,IL-7Rα
Background: CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.
Gene ID: 3575
SwissProt: P16871
Buffer: PBS with 0.05% Proclin300, 1% BSA
Storage: Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Documents: Please contact us to request the manual

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