PE/Cyanine5 Anti-Human/Mouse/Rat CD47 Antibody (20 T)

PE/Cyanine5 Anti-Human/Mouse/Rat CD47 Antibody (20 T)

Cat. #: FD2568
Availability: In Stock
$289.00
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Reactivity: Human, Mouse, Rat    
Applications: FCM    
Host Species: Mouse    
Isotype: Mouse IgG1, κ    
Clonality: Monoclonal    
Conjugation: PE/Cyanine5    
Synonyms: Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP
Background: CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.
Gene ID: 961,16423,29364
SwissProt: Q08722,Q61735,P97829
Buffer: PBS with 0.05% Proclin300, 1% BSA
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Documents: Please contact us to request the manual

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