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Reactivity: | Human, Monkey |
Applications: | FCM |
Host Species: | Mouse |
Isotype: | Mouse IgG2a, κ |
Clonality: | Monoclonal |
Conjugation: | Unconjugated |
Synonyms: | CD40L, gp39, TRAP, T-BAM, TNFSF5 |
Background: | CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells. |
Gene ID: | 959 |
SwissProt: | P29965 |
Concentration: | 0.5 mg/mL |
Buffer: | PBS with 0.05% Proclin300 |
Storage: | Store at 2~8°C. Do not freeze. |
Documents: | Please contact us to request the manual |