Reactivity: | M,R |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | GADD45G/CR6 rabbit polyclonal |
Gene Name: | Growth arrest and DNA damage-inducible protein GADD45 gamma |
Synonyms: | Cytokine-responsive protein CR6, Gadd45g, Cr6, DDIT-2, DNA damage-inducible transcript 2 protein, GRP17 |
Immunogen: | Recombinant protein corresponding to Mouse GADD45G/CR6 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 2000-1: 4000 | cerebellum |
Background
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
Images
Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using GADD45G (GB113573) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded rat cerebellum using GADD45G (GB113573) at dilution of 1: 4000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |