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| Reactivity: | R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GCKR rabbit polyclonal antibody |
Gene Name: | Glucokinase regulatory protein |
Synonyms: | GCKR, KHS, KHS1, MAP4K5, MAPKKKK5, MEK kinase kinase 5, MEKKK 5 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GCKR |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 65 kDa |
Observed MW. | 65 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Rat | 1: 1000-1: 3000 | liver |
IHC/IF | Mouse, Rat | 1: 1000-1: 3000 | liver |
Background
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Images
 | Western blot analysis of GCKR (GB113849) at dilution of 1: 3000 |
 | Immunohistochemistry analysis of paraffin-embedded mouse liver using GCKR (GB113849) at dilution of 1: 3000 |
 | Immunohistochemistry analysis of paraffin-embedded rat liver using GCKR (GB113849) at dilution of 1: 3000 |
 | Immunofluorescent analysis of paraformaldehyde-fixed mouse liver using GCKR (GB113849) at dilution of 1: 3000 |
 | Immunofluorescent analysis of paraformaldehyde-fixed rat liver using GCKR (GB113849) at dilution of 1: 3000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
