Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | GHRH rabbit polyclonal antibody |
Gene Name: | Somatoliberin |
Synonyms: | Growth hormone-releasing factor, Growth hormone-releasing hormone, GRF, GHRH, INN, Sermorelin, Somatorelin, Somatocrinin |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GHRH |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 12 kDa |
Observed MW. | 12 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1500 | liver, uterus |
Background
This gene encodes a member of the glucagon family of proteins. The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor, known as somatoliberin, which acts to stimulate growth hormone release from the pituitary gland. Variant receptors for somatoliberin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Images
Western blot analysis of GHRH (GB113837) at dilution of 1: 1500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |