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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GHRHR rabbit polyclonal antibody |
Gene Name: | Growth hormone-releasing hormone receptor |
Synonyms: | Ghrhr, GHRHR, GHRFR, GRFR, IGHD1B, Growth hormone releasing hormone receptor, IGHD4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GHRHR |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 47 kDa |
Observed MW. | 52 kDa |
Uniprot ID: | P32082, Q02644 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, cerebellum, pituitary gland |
Background
The growth-hormone-releasing hormone receptor (GHRHR), expressed in the pituitary, is a G-protein-coupled receptor that binds growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. The GHRHR activates a Gs protein that causes a cascade of cAMP via Adenylate cyclase. Mutations in this gene have been associated with isolated growth-hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature.
Images
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Western blot analysis of GHRHR (GB11735) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
