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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GLRB rabbit polyclonal antibody |
Gene Name: | Glycine receptor subunit beta |
Synonyms: | Glycine receptor 58 kDa subunit, Glrb, HKPX2, Glycine receptor subunit beta |
Immunogen: | Recombinant protein corresponding to Mouse GLRB |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | P48168, P20781 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | brain, spinal cord |
Background
This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Glycine is an inhibitory neurotransmitter in the central nervous system. The glycine receptor (GlyR) is a member of the nicotinic acetylcholine receptor of ligand-gated ion channels.
Images
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Immunohistochemistry of paraffin embedded mouse spinal cord using GLRB (GB111535) at dilution of 1:1000 (200x lens) |
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Immunohistochemistry of paraffin embedded rat brain using GLRB (GB111535) at dilution of 1:1000 (300x lens) |
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Immunofluorescence of paraffin embedded mouse brain using GLRB (GB111535) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
