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Anti-GPA33 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GPA33 rabbit polyclonal |
Gene Name: | Cell surface A33 antigen |
Synonyms: | Glycoprotein A33, mA33, Gpa33, A33, Transmembrane glycoprotein A33, Cell surface A33 antigen precursor |
Immunogen: | Recombinant protein corresponding to Mouse GPA33 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell Membrane |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 1500-1: 3000 | colon, duodenum, rectum, stomach |
Background
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse colon using GPA33 (GB112051) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin-embedded rat colon using GPA33 (GB112051) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin-embedded mouse rectum using GPA33 (GB112051) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin-embedded rat rectum using GPA33 (GB112051) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin-embedded mouse stomach using GPA33 (GB112051) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin-embedded rat duodenum using GPA33 (GB112051) at dilution of 1: 3000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
