Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | GSDMC rabbit polyclonal antibody |
Gene Name: | Gasdermin-C |
Synonyms: | Gasdermin-C1, Melanoma-derived leucine zipper-containing extranuclear factor, mMLZE, Gsdmc, Gasdermin-C |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GSDMC |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 53 kDa |
Observed MW. | 70 kDa |
Uniprot ID: | Q9BYG8, Q99NB5, P85967 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | skin, kidney |
Background
The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores. The physiological relevance of this observation is unknown.
Images
Western blot analysis of GSDMC (GB111623) at dilution of 1: 50 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |