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Anti-Galactose mutarotase Rabbit pAb (100 μl)
| Reactivity: | H & H |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Galactose mutarotase |
Synonyms: | Aldose 1 epimerase, BLOCK25, Galactose mutarotase, GALM, IBD1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Galactose mutarotase |
Uniprot ID: | Q8K157 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. / Observed MW. | 38 kDa / 38 kDa |
Product Usage Information
WB | Human | 1: 500-1: 1000 | HeLa, A431, HepG2 |
IHC/IF | Human | 1: 1000-1: 2000 | renal carcinoma |
Background
Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism. Beta-D-galactose is metabolized in the liver into glucose 1-phosphate, the primary metabolic fuel, by the action of four enzymes that constitute the Leloir pathway: GALM, GALK1 (galactokinase), GALT (galactose-1-phosphate uridylyltransferase) and GALE (UDP-galactose-4'-epimerase). Involved in the maintenance of the equilibrium between the beta- and alpha-anomers of galactose, therefore ensuring a sufficient supply of the alpha-anomer for GALK1. Also active on D-glucose although shows a preference for galactose over glucose.
Images
| Western blot analysis of GALM (GB114869) at dilution of 1: 100 |
| Immunohistochemistry analysis of paraffin embedded human renal carcinoma using GALM (GB114869) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
