Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Galectin 3 rabbit polyclonal antibody |
Gene Name: | Galectin-3 |
Synonyms: | LGALS3, CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2, lectin, Galactoside binding soluble 3, Galectin 3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Galectin 3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 26 kDa |
Observed MW. | 30 kDa |
Uniprot ID: | P17931, P08699, P16110 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 1500 | lung, colon |
Background
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Images
Western blot analysis of Galectin-3 (GB11940) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |