Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Gmfg rabbit polyclonal antibody |
Gene Name: | Glia maturation factor gamma |
Synonyms: | GMF-gamma, Gmfg, gamma, Glia maturation factor |
Immunogen: | Recombinant protein corresponding to Mouse Gmfg |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 17 kDa |
Observed MW. | 17 kDa |
Uniprot ID: | O60234, Q9ERL7, Q80T18 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 250-1: 500 | thymus |
Background
GMF-gamma is a 142 amino acid protein that belongs to the GMF subfamily of the larger actin-binding protein ADF family. GMF-gamma is expressed predominantly in lung, heart and placenta. GMF-gamma is considered a candidate regulatory growth factor protein, mediating both paracrine and autocrine cell-cell interactions. GMF-gamma is phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac 1 and Cdc42. As a regulator of actin-based cellular functions, GMF-gamma may provide a novel approach to modulate the pathophysiology of cardiovascular diseases. GMF-gamma is primarily found in proliferative and differentiative organs.
Images
Western blot analysis of GMFG (GB112242) at dilution of 1: 250 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |