Your shopping cart is empty!
| Reactivity: | M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Histone deacetylase 1 |
Synonyms: | HDAC1, GON-10, HD1, RPD3, RPD3L1, histone deacetylase 1 |
Immunogen: | Recombinant protein corresponding to Mouse HDAC1 |
Uniprot ID: | O09106 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. / Observed MW. | 55 kDa / 62 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | testis, thymus |
IHC/IF | Human, Mouse, Rat | 1: 1000-1: 2000 | heart, testis, brain, kidney ,lung cancer ,liver cancer ,colon cancer ,ovary cancer |
Background
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2 MTA2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Images
|
|
Western blot analysis of HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunohistochemistry analysis of paraffin embedded human lung cancer using HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunohistochemistry analysis of paraffin embedded human liver cancer using HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunohistochemistry analysis of paraffin embedded human colon cancer using HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunohistochemistry analysis of paraffin embedded human ovary cancer using HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunohistochemistry analysis of paraffin embedded mouse heart using HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunohistochemistry analysis of paraffin embedded mouse testis using HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunohistochemistry analysis of paraffin embedded rat testis using HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunohistochemistry analysis of paraffin embedded mouse brain using HDAC1 (GB12333) at dilution of 1: 2000 |
|
|
Immunohistochemistry analysis of paraffin embedded rat brain using HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunohistochemistry analysis of paraffin embedded mouse kidney using HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunofluorescent analysis of paraformaldehyde-fixed human small intestine cancer using HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunofluorescent analysis of paraformaldehyde-fixed rat brain using HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunofluorescent analysis of paraformaldehyde-fixed rat colon using HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunofluorescent analysis of paraformaldehyde-fixed rat brain using HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunofluorescent analysis of paraformaldehyde-fixed rat kidney using HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunofluorescent analysis of paraformaldehyde-fixed rat lung using HDAC1 (GB12333) at dilution of 1: 1000 |
|
|
Immunofluorescent analysis of paraformaldehyde-fixed rat testis using HDAC1 (GB12333) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
