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Anti-HINT1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Histidine triad nucleotide-binding protein 1 |
Synonyms: | Adenosine 5'-monophosphoramidase, Protein kinase C inhibitor 1, Protein kinase C-interacting protein 1, PKCI-1, Hint1, Hint, Pkci, Pkci1, Prkcnh1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse HINT1 |
Uniprot ID: | P70349 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. / Observed MW. | 14 kDa / 14 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 1500-1: 3000 | brain, liver |
IHC/IF | Human, Rat | 1: 500-1: 1000 | colon cancer, kidney |
Background
The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumor suppressing gene.
Images
| Western blot analysis of HINT1 (GB112011) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human colon cancer using HINT1 (GB112011) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded rat kidney using HINT1 (GB112011) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
