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Anti-HNF1 alpha Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | HNF1 alpha rabbit polyclonal antibody |
Gene Name: | Hepatocyte nuclear factor 1-alpha |
Synonyms: | HNF-1-alpha, HNF-1A, Liver-specific transcription factor LF-B1, LFB1, Transcription factor 1, TCF-1, Hnf-1, Hnf-1a, Tcf1, Hnf1a |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse HNF1 alpha |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 57 kDa |
Observed MW. | 81 kDa |
Uniprot ID: | P22361, P15257 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | pancreas, prostate, liver |
Background
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
Images
| Western blot analysis of TCF1 (GB112214) at dilution of 1: 500 |
| Western blot analysis of TCF1 (GB112214) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
