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Anti-HOMER3 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Homer protein homolog 3 |
Synonyms: | Homer-3, HOMER 3, homer homolog 3 (Drosophila), VESL3, Homer 3D protein |
Immunogen: | Recombinant protein corresponding to Mouse HOMER3 |
Uniprot ID: | Q99JP6 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. / Observed MW. | 40 kDa / 40 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 1000-1: 2000 | brain, lung, spleen, cerebellum |
IHC/IF | Mouse, Rat | 1: 700-1: 2100 | cerebellum, placenta, spleen |
Background
HOMER3 is a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling.
Images
| Western blot analysis of HOMER3 (GB111825) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat spleen using HOMER3 (GB111825) at dilution of 1: 2100 |
| Immunohistochemistry analysis of paraffin embedded rat plancta using HOMER3 (GB111825) at dilution of 1: 2100 |
| Immunohistochemistry analysis of paraffin embedded rat cerebellum using HOMER3 (GB111825) at dilution of 1: 2100 |
| Immunohistochemistry analysis of paraffin embedded mouse cerebellum using HOMER3 (GB111825) at dilution of 1: 2100 |
| Immunofluorescent analysis of paraffin embedded rat spleen using HOMER3 (GB111825) at dilution of 1: 700 |
| Immunofluorescent analysis of paraffin embedded rat plancta using HOMER3 (GB111825) at dilution of 1: 700 |
| Immunofluorescent analysis of paraffin embedded rat cerebellum using HOMER3 (GB111825) at dilution of 1: 700 |
| Immunofluorescent analysis of paraffin embedded mouse cerebellum using HOMER3 (GB111825) at dilution of 1: 700 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
