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Anti-HOOK1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | HOOK1 rabbit polyclonal antibody |
Gene Name: | Protein Hook homolog 1 |
Synonyms: | h-hook1, hHK1, HK1, hook homolog 1 (Drosophila), HOOK1, azh, Abnormal spermatozoon head shape |
Immunogen: | Recombinant protein corresponding to Mouse HOOK1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: | Q8BIL5 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 1000-1: 2000 | testis |
Background
Component of the FTS/Hook/FHIP complex (FHF complex).The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell (By similarity). Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton.
Images
| Immunohistochemistry analysis of paraffin embedded mouse testis using HOOK1 (GB114077) at dilution of 1: 1500 |
| Immunohistochemistry analysis of paraffin embedded rat testis using HOOK1 (GB114077) at dilution of 1: 1500 |
| Immunofluorescence of paraffin embedded mouse testis using HOOK1 (GB114077) at dilution of 1: 1000 |
| Immunofluorescence of paraffin embedded rat testis using HOOK1 (GB114077) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
