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Anti-HSD17B3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Testosterone 17-beta-dehydrogenase 3 |
Synonyms: | 17 beta HSD 3, EDH17B3, HSD17B3, SDR12C2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse HSD17B3 |
Uniprot ID: | P70385 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 34 kDa / 40 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 800-1: 1200 | testis, brain, liver |
Background
Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH. Androgens such as epiandrosterone, dehydroepiandrosterone, androsterone and androstanedione are accepted as substrates and reduced at C-17. Can reduce 11-ketoandrostenedione as well as 11beta-hydroxyandrostenedione at C-17 to the respective testosterone forms.
Images
| Western blot analysis of HSD17B3 (GB114672) at dilution of 1: 1200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
