Anti-Heme Oxygenase 1 Rabbit pAb (100 μl)

Anti-Heme Oxygenase 1 Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB11549-100
Availability: In Stock
$259.00
-+
Reactivity: Mouse, Rat    
Applications: IHC    
Host Species: Rabbit    
Clonality: Polyclonal antibody    
Gene Name: heme oxygenase 1
Gene Symbol: Hmox1
Synonyms: HO1; HO-1; Hmox; Hemox; Hsp32; D8Wsu38e
Gene ID: 15368P14901
>Uniprot ID: P14901
Immunogen: Recombinant protein corresponding to Mouse HMOX1
Isotype: IgG
Purity: Affinity purification
Subcellular location: Endoplasmic reticulum
Documents: Manual-Hmox1 polyclonal antibody




Product Usage Information

Applications

Species

Dilution

Positive Sample

IHC

Mouse, Rat

1: 600-1: 1600

lung, spleen




Background

Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.




Images


Immunohistochemistry of paraffin embedded mouse spleen using HMOX1 (GB11549) at dilution of 1:600 (400x lens)

Immunohistochemistry of paraffin embedded rat spleen using HMOX1 (GB11549) at dilution of 1:600 (400x lens)

Immunofluorescence of paraffin embedded mouse spleen using HMOX1 (GB11549) at dilution of 1:600 (400x lens)

Immunofluorescence of paraffin embedded rat lung using HMOX1 (GB11549) at dilution of 1:600 (400x lens)

Immunofluorescence of paraffin embedded rat spleen using HMOX1 (GB11549) at dilution of 1:600 (400x lens)




Storage

StorageStore at -20°C for one year. Avoid repeated freeze/ thaw cycles.
Storage BufferPBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


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