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Anti-Hsc70 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Heat shock cognate 71 kDa protein |
Synonyms: | Heat shock 70 kDa protein 8, Hspa8, Hsc70, Hsc73, Constitutive heat shock protein 70, HSPA10, LAP1, NIP71, N-myristoyltransferase inhibitor protein 71 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Hsc70 |
Uniprot ID: | P63017 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 71 kDa / 71 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 100-1: 500 | heart, lung, brain |
Background
HSPA8 (also known as HSC70) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA8 is a constitutively expressed cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Recently it has been reported that HSPA8 can interact with α-synuclein, the critical pathological protein of Parkinson’s disease, indicating its implication in neurodegenerative disease.
Images
| Western blot analysis of Hsc70 (GB111799) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
