Anti-Hsp27 Rabbit pAb (100 μl)

Anti-Hsp27 Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB111176-100
Availability: In Stock
$259.00
-+
Reactivity: H & H    
Applications: WB & IHC/IF    
Host Species: Rabbit    
Clonality: Polyclonal    
Full Name:

Hsp27 rabbit polyclonal antibody

Gene Name:

Heat shock protein beta-1

Synonyms:

HspB1, Estrogen-regulated 24 kDa protein, 28 kDa heat shock protein, Heat shock 27 kDa protein, HSP27, Stress-responsive protein 27, SRP27, HSP28

Immunogen:

Recombinant protein corresponding to Human Hsp27

Isotype:

IgG

Purity:

Affinity purification

Subcellular location:

Nucleus, Cytoplasm

Predicted MW.

23 kDa

Observed MW.

27 kDa

Uniprot ID:

P04792





Images

Applications

Species

Dilution

Positive tissue

WB

Human

1: 10000-1: 20000

HeLa, MCF7, A549, SH-SY5Y, SKOV3

IHC/IF

Human

1: 1000-1: 3000

breast cancer, lung cancer





Background

HSPB1, also known as heat shock protein 27 (Hsp27), belongs to the small heat shock protein family which is induced in response to environmental challenges or/and developmental transitions. It is also an anti-apoptotic protein that plays crucial roles in tumorigenesis and cell survival and is reported to be an independent prognosis marker for cancer. Recently HSPB1 has been found to be a valuable marker for melanoma.




Images

Western blot analysis of HSP27 (GB111176) at dilution of 1: 10000

Immunohistochemistry of paraffin embedded human breast cancer using HSP27 (GB111176) at dilution of 1: 1500 (400x lens)

Immunohistochemistry of paraffin embedded human lung cancer using HSP27 (GB111176) at dilution of 1: 1500 (400x lens)




Storage

Storage Store at -20°C for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


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