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Anti-IDH3B Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IDH3B rabbit polyclonal antibody |
Gene Name: | Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial |
Synonyms: | H-IDHB, Idh3B, Isocitric dehydrogenase, Isocitric dehydrogenase subunit beta, RP46, NAD+-specific isocitrate dehydrogenase beta, NAD(+)-specific ICDH |
Immunogen: | Recombinant protein corresponding to Human IDH3B |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Mitochondrion |
Predicted MW. | 42 kDa |
Observed MW. | 42 kDa |
Uniprot ID: | O43837 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 2000-1: 4000 | colon, testis, lung |
IHC/IF | Human, Mouse, Rat | 1: 1800-1: 3600 | kidney, colon, placenta, heart, testis |
Background
Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
Images
 | Western blot analysis of IDH3B (GB114009) at dilution of 1: 2000 |
 | Immunohistochemistry of paraffin embedded human colon using IDH3B (GB114009) at dilution of 1: 2400 |
 | Immunohistochemistry of paraffin embedded human kidney using IDH3B (GB114009) at dilution of 1: 2400 |
 | Immunohistochemistry of paraffin embedded mouse kidney using IDH3B (GB114009) at dilution of 1: 2400 |
 | Immunohistochemistry of paraffin embedded rat kidney using IDH3B (GB114009) at dilution of 1: 2400 |
 | Immunohistochemistry of paraffin embedded human plancta using IDH3B (GB114009) at dilution of 1: 2400 |
 | Immunohistochemistry of paraffin embedded rat heart using IDH3B (GB114009) at dilution of 1: 2400 |
 | Immunohistochemistry of paraffin embedded rat testis using IDH3B (GB114009) at dilution of 1: 2400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
