Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | IL-17B Receptor rabbit polyclonal antibody |
Gene Name: | Interleukin-17 receptor B |
Synonyms: | Il17rb, IL17RB, CRL4, EVI27, IL17BR, IL17RH1, interleukin 17 receptor B |
Immunogen: | Recombinant protein corresponding to Mouse L-17B Receptor |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 56 kDa |
Observed MW. | 65 kDa |
Uniprot ID: | Q9NRM6, Q9JIP3 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, lung, kidney |
Background
Interleukin-17 receptor B is a cytokine receptor. This receptor specifically binds to IL17B and IL17E (IL25), but does not bind to IL17(A) or IL17C. This receptor has been shown to mediate the activation of NF-κB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.
Images
Western blot analysis of IL-17RB (GB11658) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |