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Anti-IL-17RC Rabbit pAb (100 μl)
| Reactivity: | R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IL-17RC rabbit polyclonal antibody |
Gene Name: | Interleukin-17 receptor C |
Synonyms: | IL-17 receptor C, IL-17RC, Interleukin-17 receptor-like protein, IL-17RL, ZcytoR14, Il17rc, Interleukin 17 receptor homolog |
Immunogen: | Recombinant protein corresponding to Mouse IL-17RC |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 77 kDa |
Observed MW. | 72 kDa |
Uniprot ID: | Q8K4C2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Rat | 1: 500-1: 1000 | skin, lung |
Background
This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases.
Images
| Western blot analysis of IL17RC (GB111637) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
