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Anti-IL3RA/CD123 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IL3RA/CD123 rabbit polyclonal antibody |
Gene Name: | Interleukin-3 receptor subunit alpha |
Synonyms: | CD123, hIL 3Ra, IL-3 receptor subunit alpha, IL 3R alpha, IL-3R subunit alpha, IL-3RA, IL3R, IL3RA, IL-3RA, IL3RAY, IL3RX, IL3RY |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse IL3RA/CD123113822 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 43 kDa |
Observed MW. | 72 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 300-1: 1000 | 8226, THP-1, U-87MG |
Background
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.
Images
 | Western blot analysis of IL3RA (GB113822) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
