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Anti-IQGAP3 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IQGAP3 rabbit polyclonal antibody |
Gene Name: | Ras GTPase-activating-like protein IQGAP3 |
Synonyms: | IQGAP3, IQ motif containing GTPase activating protein 3, MGC1947 |
Immunogen: | Recombinant protein corresponding to Human IQGAP3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Uniprot ID: | Q86VI3 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 700-1: 1400 | placenta |
Background
IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Images
| Immunohistochemistry of paraffin embedded human placenta using IQGAP3 (GB111751) at dilution of 1:700 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
