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Anti-IRBIT Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | S-adenosylhomocysteine hydrolase-like 1 |
Synonyms: | AdoHcyase 2, AHCYL1, DCAL, IRBIT, PRO0233, XPVKONA |
Immunogen: | Recombinant protein corresponding to Mouse IRBIT |
Uniprot ID: | Q80SW1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Endoplasmic reticulum, Cytoplasm |
Product Usage Information
IHC/IF | Human | 1: 1000-1: 2000 | pancreas |
Background
S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1), also known as IP3 receptor-binding protein released with IP3 (IRBIT), regulates IP3-induced Ca2+ release into the cytoplasm of cells(PMID:23145124). This protein is also named as DCAL, XPVKONA and belongs to the adenosylhomocysteinase family. AHCYL1 mRNA and protein are most abundant in the glandular epithelium of adenocarcinoma of cancerous, but not normal and AHCYL1 protein is predominantly in the nucleus(PMID:22826361). It has 2 isoforms produced by alternative splicing.
Images
| Immunohistochemistry analysis of paraffin embedded human pancreas using AHCYL1 (GB114163) at dilution of 1: 1000 |
| Immunofluorescence analysis of paraffin embedded human pancreas using AHCYL1 (GB114163) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
