Your shopping cart is empty!
| Reactivity: | M,R & H,M |
| Applications: | WB & ICC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IVD rabbit polyclonal antibody |
Gene Name: | Isovaleryl-CoA dehydrogenase, mitochondrial |
Synonyms: | IVD, ACAD2; FLJ12715; FLJ34849, Isovaleryl Coenzyme A dehydrogenase |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse IVD |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 46 kDa |
Observed MW. | 46 kDa |
Uniprot ID: | Q9JHI5, P12007 |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | liver, heart, kidney |
ICC/IF | Human, Mouse | 1: 50-1: 200 | HeLa, NIH-3T3 |
Background
Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia.
Images
|
|
Western blot analysis of IVD (GB111309) at dilution of 1: 500 |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed HeLa cells using IVD(GB111309) at dilution of 1: 50-1: 200 |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed NIH-3T3 cells using IVD(GB111309) at dilution of 1: 50-1: 200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
