Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Integrin alpha 4 rabbit polyclonal antibody |
Gene Name: | Integrin alpha-4 |
Synonyms: | ITGA4, CD49D, IA4, integrin subunit alpha 4 |
Immunogen: | Recombinant protein corresponding to Human Integrin alpha 4 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 116 kDa |
Observed MW. | 150 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 1000-1: 2000 | Jurkat, THP-1, A20, thymus, lymph |
Background
CD49d is an integrin alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor. The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain. CD49d has been shown to interact with LGALS8 and Paxillin.
Images
Western blot analysis of Pim1 (GB11652) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |