Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Itgb1bp1 rabbit polyclonal antibody |
Gene Name: | Integrin beta-1-binding protein 1 |
Synonyms: | ICAP-1, ICAP-1A, ICAP 1alpha, ICAP-1B, ICAP1, ICAP1A, ICAP1B, ITGB1BP1 |
Immunogen: | Recombinant protein corresponding to Mouse Itgb1bp1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 22 kDa |
Observed MW. | 22 kDa |
Uniprot ID: | O35671 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 300-1: 600 | brain, thymus |
Background
ITGB1BP1, also named as ICAP1, is a key regulator of the integrin-mediated cell-matrix interaction signaling by binding to the ITGB1 cytoplasmic tail. It plays a role in cell proliferation, differentiation, spreading, adhesion and migration in the context of mineralization and bone development and angiogenesis. ITGB1BP1 promotes transcriptional activity of the MYC promoter.
Images
Western blot analysis of Itgb1bp1 (GB114012) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |