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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | JAK2 rabbit polyclonal antibody |
Gene Name: | Tyrosine-protein kinase JAK2 |
Synonyms: | JAK2, JTK10, THCYT3, Janus kinase 2, MAX2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse JAK2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 130 kDa |
Observed MW. | 130 kDa |
Uniprot ID: | Q62120, Q62689 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | spleen, lymph node, lung |
Background
Janus kinase 2 (commonly called JAK2) is a non-receptor tyrosine kinase. It is a member of the Janus kinasefamily and has been implicated in signaling by members of the type II cytokine receptor family (e.g.interferon receptors), the GM-CSF receptor family (IL-3R, IL-5R and GM-CSF-R), the gp130 receptor family (e.g., IL-6R), and the single chain receptors (e.g. Epo-R, Tpo-R, GH-R, PRL-R). JAK2 signaling is activated downstream from the prolactin receptor.
Images
| Western blot analysis of JAK2 (GB11325) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
