Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Keratin 12/K12 rabbit polyclonal antibody |
Gene Name: | Keratin, type I cytoskeletal 12 |
Synonyms: | Cytokeratin-12, CK-12, Keratin-12, K12, Krt12, rt1-12, Krt1.12 |
Immunogen: | Recombinant protein corresponding to Mouse Keratin 12/K12 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoskeleton |
Uniprot ID: | Q64291 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Rat | 1: 100-1: 600 | eye |
Background
KRT12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Mutations in this gene lead to Meesmann corneal dystrophy.May play a unique role in maintaining the normal corneal epithelial function. Together with KRT3, essential for the maintenance of corneal epithelium integrity.
Images
Immunohistochemistry of paraffin embedded rat eye using Keratin-12 (GB111820) at dilution of 1:300 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |