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Anti-KAT13D / CLOCK Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Circadian locomoter output cycles protein kaput |
Synonyms: | Mclock, Clock, bHLHe8, clock homolog (mouse), hCLOCK, KAT13D, KIAA0334, Class E basic helix-loop-helix protein 8, KAT13D / CLOCK |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse KAT13D / CLOCK |
Uniprot ID: | O08785 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 96 kDa / 96 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | skeletal muscle, testis, heart |
Background
This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Circadian locomoter output cycles protein kaput (CLOCK), also named as BHLHE8 or KIAA0334, is a 846 amino acid protein, which contains one bHLH domain, one PAC domain, and two PAS domains. ARNTL/2-CLOCK heterodimers activate E-box element (5'-CACGTG-3') transcription of a number of proteins of the circadian clock, such as PER1 and PER2. The calculated molecular weight of CLOCK is 95kDa, we detected a 95-110 kDa protein by western blot.
Images
| Western blot analysis of KAT13D / CLOCK (GB111884) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
