Reactivity: | R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | KCNJ5 rabbit polyclonal antibody |
Gene Name: | G protein-activated inward rectifier potassium channel 4 |
Synonyms: | GIRK-4, Cardiac inward rectifier, Heart KATP channel, CIR, KATP-1, Heart KATP channel, Kcnj5, Girk4, Inward rectifier K(+) channel Kir3.4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse KCNJ5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Rat | 1: 400-1: 800 | heart |
Background
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.
Images
Immunohistochemistry analysis of paraffin embedded rat heart using KCNJ5 (GB113854) at dilution of 1: 800 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |