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KO-Validated HNRNPR Rabbit pAb (20 μl)
| Reactivity: | Human |
| Applications: | WB, IF/ICC, ELISA |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Polyclonal antibody |
| Gene Name: | heterogeneous nuclear ribonucleoprotein R |
| Gene Symbol: | HNRNPR |
| Synonyms: | HNRPR; NEDDFSB; hnRNP-R; PR |
| Gene ID: | 10236 |
| UniProt ID: | O43390 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 550-633 of human HNRNPR (NP_005817.1). |
| Dilution: | WB 1:1000-1:6000; IHC 1:200-1:800 |
| Purification Method: | Affinity purification |
| Concentration: | 0.86 mg/mL |
| Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-HNRNPR polyclonal antibody |
Background
This gene encodes an RNA-binding protein that is a member of the spliceosome C complex, which functions in pre-mRNA processing and transport. The encoded protein also promotes transcription at the c-fos gene. Alternative splicing results in multiple transcript variants. There are pseudogenes for this gene on chromosomes 4, 11, and 10.
Images
 | Western blot analysis of lysates from wild type (WT) and HNRNPR knockout (KO) 293T cells, using [KO Validated] HNRNPR Rabbit pAb (A19999) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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