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Anti-KDELR3 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | KDELR3 rabbit polyclonal antibody |
Gene Name: | ER lumen protein-retaining receptor 3 |
Synonyms: | KDEL endoplasmic reticulum protein retention receptor 3, KDEL receptor 3, Kdelr3, ERD2L3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse KDELR3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 25 kDa |
Observed MW. | 28 kDa |
Uniprot ID: | O43731, Q8R1L4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 2000-1: 4000 | prostate, pancreas, lymph node, spleen |
Background
This gene encodes a member of the KDEL endoplasmic reticulum protein retention receptor family. Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. KDELR3 was the third member of the family to be identified. Alternate splicing results in multiple transcript variants.
Images
 | Western blot analysis of KDELReceptor3 (GB112573) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
