Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | KIF5A rabbit polyclonal antibody |
Gene Name: | Kinesin heavy chain isoform 5A |
Synonyms: | D12S1889, KIF5A, kinesin family member 5A, MY050, Neuronal kinesin heavy chain, NKHC, NKHC1, SPG10 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse KIF5A |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 117 kDa |
Observed MW. | 130 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | brain |
Background
Kinesin superfamily proteins (KIFs) are microtubule-based molecular motors essential for the intracellular transport of various cargos, including organelles, proteins, and RNAs. KIF5A is expressed exclusively in neurons and transports neuronal cargoes into axons and dendrites. KIF5A mutations have been associated with Charcot-Marie-Tooth Type 2, an axonal peripheral neuropathy characterized by progressive loss of peripheral sensation and muscle wasting.
Images
Western blot analysis of KIF5A (GB113814) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |