KO-Validated CBR1 Rabbit pAb (20 μl)

KO-Validated CBR1 Rabbit pAb (20 μl)

Brand: Abclonal
Cat. #: A18074
Availability: In Stock
$128.00
-+
Reactivity: Human    
Applications: WB, ELISA    
Host Species: Rabbit    
Isotype: IgG    
Clonality: Polyclonal antibody    
Gene Name: carbonyl reductase 1
Gene Symbol: CBR1
Synonyms: CBR; hCBR1; PG-9-KR; SDR21C1; R1
Gene ID: 873
UniProt ID: P16152
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human CBR1 (NP_001748.1).
Dilution: WB 1:500-1:2000
Purification Method: Affinity purification
Concentration: 0.96 mg/mL
Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Documents: Manual-CBR1 polyclonal antibody




Background

The protein encoded by the gene CBR1 belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene.




Images

CBR1 rabbit pAbWestern blot analysis of lysates from wild type (WT) and CBR1 knockout (KO) A-549 cells, using [KO Validated] CBR1 Rabbit pAb (A18074) at 1:3000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 5s.



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