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| Reactivity: | Human |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Polyclonal antibody |
| Gene Name: | serine/threonine kinase receptor associated protein |
| Gene Symbol: | STRAP |
| Synonyms: | MAWD; PT-WD; UNRIP; AP |
| Gene ID: | 11171 |
| UniProt ID: | Q9Y3F4 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human STRAP (NP_009109.3). |
| Dilution: | WB 1:1000-1:2000 |
| Purification Method: | Affinity purification |
| Concentration: | 2.17 mg/mL |
| Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-STRAP polyclonal antibody |
Background
Enables RNA binding activity. Involved in maintenance of gastrointestinal epithelium; negative regulation of transforming growth factor beta receptor signaling pathway; and spliceosomal snRNP assembly. Located in cytosol. Part of SMN complex. Implicated in adenocarcinoma; colorectal carcinoma; large cell carcinoma; lung carcinoma; and squamous cell neoplasm.
Images
_KO-WB_01.jpg?t=1711068996) | Western blot analysis of lysates from wild type (WT) and STRAP knockout (KO) 293T cells, using [KO Validated] STRAP Rabbit pAb (A19989) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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