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Anti-KRT81 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | KRT81 rabbit polyclonal antibody |
Gene Name: | Keratin, type II cuticular Hb1 |
Synonyms: | Keratin-81, K81, Type II hair keratin Hb1, Krt81, Krt2-19, ghHKb1, MLN137 |
Immunogen: | Recombinant protein corresponding to Mouse KRT81 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoskeleton |
Uniprot ID: | Q14533, Q9ERE2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 400-1: 1200 | skin, thymus |
Background
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5.Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
Images
| Immunofluorescence of paraffin embedded human skin using KRT81 (GB111745) at dilution of 1:650 (300x lens) |
| Immunofluorescence of paraffin embedded mouse thymus using KRT81 (GB111745) at dilution of 1:650 (400x lens) |
 | Immunofluorescence of paraffin embedded rat thymus using KRT81 (GB111745) at dilution of 1:650 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
